{"cited_by_count":282086,"description":"This cluster of papers focuses on the diagnosis and management of IgG4-related disease, including autoimmune pancreatitis, inflammatory myofibroblastic tumor, and sclerosing cholangitis. It discusses the diagnostic criteria, pathological features, clinical profiles, and therapeutic approaches such as rituximab therapy for this systemic disease.","display_name":"IgG4-Related and Inflammatory Diseases","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T11576","wikipedia":"https://en.wikipedia.org/wiki/IgG4-related_disease"},"field_id":"27","id":"T11576","keywords":[{"display_name":"IgG4-related disease","id":"igg4-related-disease","score":0.8162,"url":"https://openalex.org/keywords/igg4-related-disease"},{"display_name":"autoimmune pancreatitis","id":"autoimmune-pancreatitis","score":0.7386,"url":"https://openalex.org/keywords/autoimmune-pancreatitis"},{"display_name":"inflammatory myofibroblastic tumor","id":"inflammatory-myofibroblastic-tumor","score":0.7418,"url":"https://openalex.org/keywords/inflammatory-myofibroblastic-tumor"},{"display_name":"retroperitoneal fibrosis","id":"retroperitoneal-fibrosis","score":0.4607,"url":"https://openalex.org/keywords/retroperitoneal-fibrosis"},{"display_name":"inflammatory pseudotumor","id":"inflammatory-pseudotumor","score":0.4831,"url":"https://openalex.org/keywords/inflammatory-pseudotumor"},{"display_name":"IgG4-positive plasma cells","id":"igg4-positive-plasma-cells","score":0.8457,"url":"https://openalex.org/keywords/igg4-positive-plasma-cells"},{"display_name":"serum IgG4","id":"serum-igg4","score":0.8118,"url":"https://openalex.org/keywords/serum-igg4"},{"display_name":"lymphoplasmacytic infiltration","id":"lymphoplasmacytic-infiltration","score":0.4217,"url":"https://openalex.org/keywords/lymphoplasmacytic-infiltration"},{"display_name":"idiopathic retroperitoneal fibrosis","id":"idiopathic-retroperitoneal-fibrosis","score":0.6878,"url":"https://openalex.org/keywords/idiopathic-retroperitoneal-fibrosis"},{"display_name":"IgG4-related sclerosing cholangitis","id":"igg4-related-sclerosing-cholangitis","score":0.7821,"url":"https://openalex.org/keywords/igg4-related-sclerosing-cholangitis"},{"display_name":"fibroinflammatory disease","id":"fibroinflammatory-disease","score":0.8761,"url":"https://openalex.org/keywords/fibroinflammatory-disease"},{"display_name":"storiform fibrosis","id":"storiform-fibrosis","score":0.9395,"url":"https://openalex.org/keywords/storiform-fibrosis"},{"display_name":"type 1 autoimmune pancreatitis","id":"type-1-autoimmune-pancreatitis","score":0.9431,"url":"https://openalex.org/keywords/type-1-autoimmune-pancreatitis"},{"display_name":"obliterative phlebitis","id":"obliterative-phlebitis","score":0.9452,"url":"https://openalex.org/keywords/obliterative-phlebitis"},{"display_name":"type 2 autoimmune pancreatitis","id":"type-2-autoimmune-pancreatitis","score":0.9491,"url":"https://openalex.org/keywords/type-2-autoimmune-pancreatitis"},{"display_name":"IgG4/IgG ratio","id":"igg4-igg-ratio","score":0.7878,"url":"https://openalex.org/keywords/igg4-igg-ratio"},{"display_name":"serum IgG4 elevation","id":"serum-igg4-elevation","score":0.9162,"url":"https://openalex.org/keywords/serum-igg4-elevation"},{"display_name":"TAFRO syndrome","id":"tafro-syndrome","score":0.6134,"url":"https://openalex.org/keywords/tafro-syndrome"},{"display_name":"Mikulicz's disease","id":"mikulicz-disease","score":0.4694,"url":"https://openalex.org/keywords/mikulicz-disease"},{"display_name":"IgG4-related kidney disease","id":"igg4-related-kidney-disease","score":0.8759,"url":"https://openalex.org/keywords/igg4-related-kidney-disease"},{"display_name":"inflammatory pseudotumor of the liver","id":"inflammatory-pseudotumor-of-the-liver","score":0.9161,"url":"https://openalex.org/keywords/inflammatory-pseudotumor-of-the-liver"},{"display_name":"IgG4-related orbital disease","id":"igg4-related-orbital-disease","score":0.8457,"url":"https://openalex.org/keywords/igg4-related-orbital-disease"},{"display_name":"lymphoplasmacytic sclerosing pancreatitis","id":"lymphoplasmacytic-sclerosing-pancreatitis","score":0.8929,"url":"https://openalex.org/keywords/lymphoplasmacytic-sclerosing-pancreatitis"},{"display_name":"IgG4-positive plasma cell infiltration","id":"igg4-positive-plasma-cell-infiltration","score":0.8872,"url":"https://openalex.org/keywords/igg4-positive-plasma-cell-infiltration"},{"display_name":"extrapancreatic manifestations","id":"extrapancreatic-manifestations","score":0.8174,"url":"https://openalex.org/keywords/extrapancreatic-manifestations"}],"legacy_keywords":["IgG4-Related Disease","Autoimmune Pancreatitis","Inflammatory Myofibroblastic Tumor","Sclerosing Cholangitis","Diagnostic Criteria","Immunoglobulin G4","Pathological Features","Rituximab Therapy","Clinical Profile","Systemic Disease"],"openalex_id":"https://openalex.org/T11576","source_created_date":"2024-01-23T15:27:11","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2745","url":"/topics/T11576","works_api_url":"https://api.openalex.org/works?filter=topics.id:T11576","works_count":24527,"label":"IgG4-Related and Inflammatory Diseases","provider":"openalex","revision":"4d8d502be91d2f90","taxonomy_revision":"f050b5d4780b1289","title":"IgG4-Related and Inflammatory Diseases","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36249009669464358","address_version":"morton4x16-v1","coordinates":[4,27,2745,11576],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}