{"cited_by_count":530081,"description":"This cluster of papers focuses on Neurofibromatosis Type 1 and Type 2, genetic disorders characterized by the development of tumors in the nervous system. The research covers various aspects including the role of tumor suppressor genes, Schwann cell origin of neurofibromas, cognitive deficits associated with the condition, and the molecular mechanisms underlying the disease.","display_name":"Neurofibromatosis and Schwannoma Cases","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T11173","wikipedia":"https://en.wikipedia.org/wiki/Neurofibromatosis"},"field_id":"27","id":"T11173","keywords":[{"display_name":"neurofibromatosis type 1","id":"neurofibromatosis-type-1","score":0.6167,"url":"https://openalex.org/keywords/neurofibromatosis-type-1"},{"display_name":"schwannoma","id":"schwannoma","score":0.5008,"url":"https://openalex.org/keywords/schwannoma"},{"display_name":"neurofibromatosis","id":"neurofibromatosis","score":0.6574,"url":"https://openalex.org/keywords/neurofibromatosis"},{"display_name":"neurofibroma","id":"neurofibroma","score":0.6708,"url":"https://openalex.org/keywords/neurofibroma"},{"display_name":"malignant peripheral nerve sheath tumor","id":"malignant-peripheral-nerve-sheath-tumor","score":0.6683,"url":"https://openalex.org/keywords/malignant-peripheral-nerve-sheath-tumor"},{"display_name":"neurofibromatosis type 2","id":"neurofibromatosis-type-2","score":0.5761,"url":"https://openalex.org/keywords/neurofibromatosis-type-2"},{"display_name":"peripheral nerve sheath tumor","id":"peripheral-nerve-sheath-tumor","score":0.7178,"url":"https://openalex.org/keywords/peripheral-nerve-sheath-tumor"},{"display_name":"plexiform neurofibroma","id":"plexiform-neurofibroma","score":0.9057,"url":"https://openalex.org/keywords/plexiform-neurofibroma"},{"display_name":"peripheral nerve tumor","id":"peripheral-nerve-tumor","score":0.6562,"url":"https://openalex.org/keywords/peripheral-nerve-tumor"},{"display_name":"caf\u00e9-au-lait spots","id":"cafe-au-lait-macules","score":0.5316,"url":"https://openalex.org/keywords/cafe-au-lait-macules"},{"display_name":"neurogenic tumors","id":"neurogenic-tumors","score":0.3772,"url":"https://openalex.org/keywords/neurogenic-tumors"},{"display_name":"NF1 gene","id":"nf1-gene","score":0.8721,"url":"https://openalex.org/keywords/nf1-gene"},{"display_name":"NF3","id":"nitrogen-trifluoride","score":0.4561,"url":"https://openalex.org/keywords/nitrogen-trifluoride"},{"display_name":"nerve sheath tumor","id":"nerve-sheath-tumor","score":0.5351,"url":"https://openalex.org/keywords/nerve-sheath-tumor"},{"display_name":"neurofibromin","id":"neurofibromin","score":0.7049,"url":"https://openalex.org/keywords/neurofibromin"},{"display_name":"cutaneous neurofibromas","id":"cutaneous-neurofibromas","score":0.9231,"url":"https://openalex.org/keywords/cutaneous-neurofibromas"},{"display_name":"schwannomatosis","id":"schwannomatosis","score":0.835,"url":"https://openalex.org/keywords/schwannomatosis"},{"display_name":"Lisch nodules","id":"lisch-nodules","score":0.8344,"url":"https://openalex.org/keywords/lisch-nodules"},{"display_name":"benign nerve sheath tumor","id":"benign-nerve-sheath-tumor","score":0.79,"url":"https://openalex.org/keywords/benign-nerve-sheath-tumor"},{"display_name":"optic nerve glioma","id":"optic-nerve-glioma","score":0.2926,"url":"https://openalex.org/keywords/optic-nerve-glioma"},{"display_name":"ganglioneuroma","id":"ganglioneuroma","score":0.2325,"url":"https://openalex.org/keywords/ganglioneuroma"},{"display_name":"retroperitoneal schwannoma","id":"retroperitoneal-schwannoma","score":0.9217,"url":"https://openalex.org/keywords/retroperitoneal-schwannoma"},{"display_name":"NF2 gene","id":"nf2-gene","score":0.7759,"url":"https://openalex.org/keywords/nf2-gene"},{"display_name":"solitary neurofibroma","id":"solitary-neurofibroma","score":0.9458,"url":"https://openalex.org/keywords/solitary-neurofibroma"},{"display_name":"benign schwannoma","id":"benign-schwannoma","score":0.8513,"url":"https://openalex.org/keywords/benign-schwannoma"}],"legacy_keywords":["Neurofibromatosis","Tumor Suppressor","Schwann Cells","Malignant Peripheral Nerve Sheath Tumors","Gliomas","Ezrin Protein","Merlin Protein","Genetic Mutations","Cognitive Deficits","Cell Cortex"],"openalex_id":"https://openalex.org/T11173","source_created_date":"2024-01-23T15:27:09","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2728","url":"/topics/T11173","works_api_url":"https://api.openalex.org/works?filter=topics.id:T11173","works_count":52538,"label":"Neurofibromatosis and Schwannoma Cases","provider":"openalex","revision":"ea37263fb5279699","taxonomy_revision":"f050b5d4780b1289","title":"Neurofibromatosis and Schwannoma Cases","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36240765478922538","address_version":"morton4x16-v1","coordinates":[4,27,2728,11173],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}