{"cited_by_count":985231,"description":"This cluster of papers explores the genetic, physiological, and environmental influences on sex determination and differentiation in various organisms. It covers topics such as X chromosome inactivation, Y chromosome degeneration, gonadal development, sexually dimorphic gene expression, Turner syndrome, SRY gene function, aromatase expression, Wnt signaling pathway, and temperature-dependent sex determination.","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","domain_id":"1","external_ids":{"openalex":"https://openalex.org/T11077","wikipedia":"https://en.wikipedia.org/wiki/Sex_determination_and_differentiation"},"field_id":"13","id":"T11077","keywords":[{"display_name":"sex determination","id":"sex-determination","score":0.2769,"url":"https://openalex.org/keywords/sex-determination"},{"display_name":"Turner syndrome","id":"turner-syndrome","score":0.453,"url":"https://openalex.org/keywords/turner-syndrome"},{"display_name":"sex chromosomes","id":"sex-chromosomes","score":0.3548,"url":"https://openalex.org/keywords/sex-chromosomes"},{"display_name":"X chromosome inactivation","id":"x-chromosome-inactivation","score":0.3192,"url":"https://openalex.org/keywords/x-chromosome-inactivation"},{"display_name":"Y chromosome","id":"y-chromosome","score":0.2877,"url":"https://openalex.org/keywords/y-chromosome"},{"display_name":"Klinefelter syndrome","id":"klinefelter-syndrome","score":0.2823,"url":"https://openalex.org/keywords/klinefelter-syndrome"},{"display_name":"sex chromosome evolution","id":"sex-chromosome-evolution","score":0.6855,"url":"https://openalex.org/keywords/sex-chromosome-evolution"},{"display_name":"sexual differentiation","id":"sexual-differentiation","score":0.2042,"url":"https://openalex.org/keywords/sexual-differentiation"},{"display_name":"sex chromosome aneuploidy","id":"sex-chromosome-aneuploidy","score":0.4785,"url":"https://openalex.org/keywords/sex-chromosome-aneuploidy"},{"display_name":"sex chromosome abnormalities","id":"sex-chromosome-abnormalities","score":0.4694,"url":"https://openalex.org/keywords/sex-chromosome-abnormalities"},{"display_name":"gonadal dysgenesis","id":"gonadal-dysgenesis","score":0.4259,"url":"https://openalex.org/keywords/gonadal-dysgenesis"},{"display_name":"dosage compensation","id":"dosage-compensation","score":0.5471,"url":"https://openalex.org/keywords/dosage-compensation"},{"display_name":"sex reversal","id":"sex-reversal","score":0.2462,"url":"https://openalex.org/keywords/sex-reversal"},{"display_name":"sex determination genes","id":"sex-determining-genes","score":0.6133,"url":"https://openalex.org/keywords/sex-determining-genes"},{"display_name":"SRY gene","id":"sry-gene","score":0.4442,"url":"https://openalex.org/keywords/sry-gene"},{"display_name":"sex chromatin","id":"barr-body","score":0.5271,"url":"https://openalex.org/keywords/barr-body"},{"display_name":"sex-biased gene expression","id":"sex-biased-gene-expression","score":0.368,"url":"https://openalex.org/keywords/sex-biased-gene-expression"},{"display_name":"SRY","id":"sry","score":0.5558,"url":"https://openalex.org/keywords/sry"},{"display_name":"sex-linked inheritance","id":"sex-linked-inheritance","score":0.2453,"url":"https://openalex.org/keywords/sex-linked-inheritance"},{"display_name":"temperature-dependent sex determination","id":"temperature-dependent-sex-determination","score":0.388,"url":"https://openalex.org/keywords/temperature-dependent-sex-determination"},{"display_name":"gonadal differentiation","id":"gonadal-differentiation","score":0.4591,"url":"https://openalex.org/keywords/gonadal-differentiation"},{"display_name":"sex-linked genes","id":"sex-linked-genes","score":0.4635,"url":"https://openalex.org/keywords/sex-linked-genes"},{"display_name":"X-linked 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Abnormalities","provider":"openalex","revision":"8a0c66a733f033b7","taxonomy_revision":"f050b5d4780b1289","title":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36174533983759951","address_version":"morton4x16-v1","coordinates":[1,13,1311,11077],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}