{"cited_by_count":2167103,"description":"This cluster of papers focuses on the development and application of mucosal drug delivery systems, with a particular emphasis on chitosan-based nanoparticles, polymeric microspheres, mucoadhesive formulations, and targeted delivery to ocular and nasal tissues. The research covers various aspects of drug release mechanisms, biodegradability, immune responses, and the potential for delivering peptides and proteins via mucosal routes.","display_name":"Advanced Drug Delivery Systems","domain_id":"1","external_ids":{"openalex":"https://openalex.org/T10920","wikipedia":"https://en.wikipedia.org/wiki/Mucosal_immunity"},"field_id":"30","id":"T10920","keywords":[{"display_name":"sustained drug release","id":"sustained-release","score":0.3334,"url":"https://openalex.org/keywords/sustained-release"},{"display_name":"controlled drug release","id":"controlled-drug-release","score":0.2443,"url":"https://openalex.org/keywords/controlled-drug-release"},{"display_name":"encapsulation efficiency","id":"encapsulation-efficiency","score":0.2217,"url":"https://openalex.org/keywords/encapsulation-efficiency"},{"display_name":"ocular drug delivery","id":"ocular-drug-delivery","score":0.6113,"url":"https://openalex.org/keywords/ocular-drug-delivery"},{"display_name":"in vitro drug release","id":"in-vitro-drug-release","score":0.4192,"url":"https://openalex.org/keywords/in-vitro-drug-release"},{"display_name":"oral drug delivery","id":"oral-drug-delivery","score":0.3658,"url":"https://openalex.org/keywords/oral-drug-delivery"},{"display_name":"intranasal drug delivery","id":"intranasal-drug-delivery","score":0.5628,"url":"https://openalex.org/keywords/intranasal-drug-delivery"},{"display_name":"mucoadhesion","id":"mucoadhesion","score":0.7237,"url":"https://openalex.org/keywords/mucoadhesion"},{"display_name":"hydroxypropyl methylcellulose","id":"hydroxypropyl-methylcellulose","score":0.3017,"url":"https://openalex.org/keywords/hydroxypropyl-methylcellulose"},{"display_name":"drug release kinetics","id":"drug-release-kinetics","score":0.3238,"url":"https://openalex.org/keywords/drug-release-kinetics"},{"display_name":"colon-targeted drug delivery","id":"colon-specific-drug-delivery","score":0.6534,"url":"https://openalex.org/keywords/colon-specific-drug-delivery"},{"display_name":"microspheres","id":"microspheres","score":0.2164,"url":"https://openalex.org/keywords/microspheres"},{"display_name":"ionic gelation","id":"ionic-gelation","score":0.4131,"url":"https://openalex.org/keywords/ionic-gelation"},{"display_name":"chitosan nanoparticles","id":"chitosan-nanoparticles","score":0.237,"url":"https://openalex.org/keywords/chitosan-nanoparticles"},{"display_name":"gastroretentive drug delivery","id":"gastroretentive-drug-delivery","score":0.8605,"url":"https://openalex.org/keywords/gastroretentive-drug-delivery"},{"display_name":"buccal drug delivery","id":"buccal-drug-delivery","score":0.8397,"url":"https://openalex.org/keywords/buccal-drug-delivery"},{"display_name":"Higuchi model","id":"higuchi-kinetics","score":0.4049,"url":"https://openalex.org/keywords/higuchi-kinetics"},{"display_name":"ethyl cellulose","id":"ethylcellulose","score":0.3399,"url":"https://openalex.org/keywords/ethylcellulose"},{"display_name":"release kinetics","id":"release-kinetics","score":0.2614,"url":"https://openalex.org/keywords/release-kinetics"},{"display_name":"matrix tablets","id":"matrix-tablets","score":0.5827,"url":"https://openalex.org/keywords/matrix-tablets"},{"display_name":"controlled drug delivery","id":"controlled-drug-delivery","score":0.2426,"url":"https://openalex.org/keywords/controlled-drug-delivery"},{"display_name":"PLGA microspheres","id":"plga-microspheres","score":0.4298,"url":"https://openalex.org/keywords/plga-microspheres"},{"display_name":"floating drug delivery systems","id":"floating-drug-delivery-systems","score":0.9104,"url":"https://openalex.org/keywords/floating-drug-delivery-systems"},{"display_name":"mucosal drug delivery","id":"mucosal-drug-delivery","score":0.6825,"url":"https://openalex.org/keywords/mucosal-drug-delivery"},{"display_name":"burst release","id":"burst-release","score":0.3869,"url":"https://openalex.org/keywords/burst-release"}],"legacy_keywords":["Chitosan","Nanoparticles","Mucosal","Drug Delivery","Polymeric","Microspheres","Mucoadhesive","Ocular","Nasal","Protein"],"openalex_id":"https://openalex.org/T10920","source_created_date":"2024-01-23T15:27:08","source_updated_date":"2026-10-17T03:02:00","subfield_id":"3003","url":"/topics/T10920","works_api_url":"https://api.openalex.org/works?filter=topics.id:T10920","works_count":118215,"label":"Advanced Drug Delivery Systems","provider":"openalex","revision":"b1d874d49f6cb21a","taxonomy_revision":"f050b5d4780b1289","title":"Advanced Drug Delivery Systems","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36240748299346533","address_version":"morton4x16-v1","coordinates":[1,30,3003,10920],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}