{"cited_by_count":4061944,"description":"This cluster of papers focuses on the structure of ribosomes, mechanisms of translation, RNA secondary structure prediction, genetic code expansion, codon usage, tRNA dynamics, and riboswitches. It explores the molecular mechanisms underlying protein synthesis and the role of RNA in regulating translation. The research also delves into the impact of ribosome structure on cellular processes and the potential applications in synthetic biology.","display_name":"RNA and protein synthesis mechanisms","domain_id":"1","external_ids":{"openalex":"https://openalex.org/T10521","wikipedia":"https://en.wikipedia.org/wiki/Ribosome"},"field_id":"13","id":"T10521","keywords":[{"display_name":"ribosome","id":"ribosome","score":0.6452,"url":"https://openalex.org/keywords/ribosome"},{"display_name":"translation initiation","id":"translation-initiation","score":0.6386,"url":"https://openalex.org/keywords/translation-initiation"},{"display_name":"RNA secondary structure","id":"rna-secondary-structure","score":0.4655,"url":"https://openalex.org/keywords/rna-secondary-structure"},{"display_name":"translational regulation","id":"translational-control","score":0.2606,"url":"https://openalex.org/keywords/translational-control"},{"display_name":"aminoacyl-tRNA synthetase","id":"aminoacyl-trna-synthetase","score":0.7567,"url":"https://openalex.org/keywords/aminoacyl-trna-synthetase"},{"display_name":"tRNA","id":"trna","score":0.5861,"url":"https://openalex.org/keywords/trna"},{"display_name":"ribosome structure","id":"ribosome-structure","score":0.9123,"url":"https://openalex.org/keywords/ribosome-structure"},{"display_name":"ribosomal proteins","id":"ribosomal-proteins","score":0.474,"url":"https://openalex.org/keywords/ribosomal-proteins"},{"display_name":"RNA folding","id":"rna-folding","score":0.7241,"url":"https://openalex.org/keywords/rna-folding"},{"display_name":"ribosomal RNA","id":"ribosomal-rna","score":0.4657,"url":"https://openalex.org/keywords/ribosomal-rna"},{"display_name":"ribosome biogenesis","id":"ribosome-biogenesis","score":0.2733,"url":"https://openalex.org/keywords/ribosome-biogenesis"},{"display_name":"codon usage bias","id":"codon-usage-bias","score":0.455,"url":"https://openalex.org/keywords/codon-usage-bias"},{"display_name":"genetic code","id":"genetic-code","score":0.4871,"url":"https://openalex.org/keywords/genetic-code"},{"display_name":"translation (biology)","id":"translation-biology","score":0.3898,"url":"https://openalex.org/keywords/translation-biology"},{"display_name":"polysomes","id":"polysomes","score":0.4492,"url":"https://openalex.org/keywords/polysomes"},{"display_name":"RNA structure","id":"rna-structure","score":0.475,"url":"https://openalex.org/keywords/rna-structure"},{"display_name":"RNA tertiary structure","id":"rna-tertiary-structure","score":0.7564,"url":"https://openalex.org/keywords/rna-tertiary-structure"},{"display_name":"ribosome assembly","id":"ribosome-assembly","score":0.709,"url":"https://openalex.org/keywords/ribosome-assembly"},{"display_name":"RNA-protein interactions","id":"protein-rna-interactions","score":0.2103,"url":"https://openalex.org/keywords/protein-rna-interactions"},{"display_name":"cell-free protein synthesis","id":"cell-free-protein-synthesis","score":0.5074,"url":"https://openalex.org/keywords/cell-free-protein-synthesis"},{"display_name":"translation elongation","id":"translation-elongation","score":0.7603,"url":"https://openalex.org/keywords/translation-elongation"},{"display_name":"codon usage","id":"codon-usage","score":0.3764,"url":"https://openalex.org/keywords/codon-usage"},{"display_name":"mRNA","id":"mrna","score":0.2656,"url":"https://openalex.org/keywords/mrna"},{"display_name":"internal ribosome entry site","id":"internal-ribosome-entry-site","score":0.4191,"url":"https://openalex.org/keywords/internal-ribosome-entry-site"},{"display_name":"tRNA modification","id":"trna-modification","score":0.5269,"url":"https://openalex.org/keywords/trna-modification"}],"legacy_keywords":["Ribosome","Translation","RNA Structure","Genetic Code","Codon Usage","tRNA","Riboswitches","Protein Synthesis","Secondary Structure Prediction","Metabolite Binding"],"openalex_id":"https://openalex.org/T10521","source_created_date":"2024-01-23T15:27:06","source_updated_date":"2026-10-17T03:02:00","subfield_id":"1312","url":"/topics/T10521","works_api_url":"https://api.openalex.org/works?filter=topics.id:T10521","works_count":157658,"label":"RNA and protein synthesis mechanisms","provider":"openalex","revision":"94119e500542241d","taxonomy_revision":"f050b5d4780b1289","title":"RNA and protein synthesis mechanisms","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36173984098198027","address_version":"morton4x16-v1","coordinates":[1,13,1312,10521],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}