{"cited_by_count":1879928,"description":"This cluster of papers focuses on the regulation of iron metabolism, including the role of hepcidin, ferroportin, and transferrin in maintaining iron homeostasis. It also explores the impact of inflammation, anemia, and oxidative stress on iron levels, as well as the association between iron deficiency and conditions such as hemochromatosis.","display_name":"Iron Metabolism and Disorders","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T10452","wikipedia":"https://en.wikipedia.org/wiki/Iron_metabolism"},"field_id":"27","id":"T10452","keywords":[{"display_name":"iron deficiency anemia","id":"iron-deficiency-anemia","score":0.4849,"url":"https://openalex.org/keywords/iron-deficiency-anemia"},{"display_name":"iron deficiency","id":"iron-deficiency","score":0.4133,"url":"https://openalex.org/keywords/iron-deficiency"},{"display_name":"iron metabolism","id":"iron-metabolism","score":0.509,"url":"https://openalex.org/keywords/iron-metabolism"},{"display_name":"iron overload","id":"iron-overload","score":0.4628,"url":"https://openalex.org/keywords/iron-overload"},{"display_name":"iron supplementation","id":"iron-supplementation","score":0.4418,"url":"https://openalex.org/keywords/iron-supplementation"},{"display_name":"serum ferritin","id":"serum-ferritin","score":0.4376,"url":"https://openalex.org/keywords/serum-ferritin"},{"display_name":"ferritin","id":"ferritin","score":0.2847,"url":"https://openalex.org/keywords/ferritin"},{"display_name":"anemia in pregnancy","id":"anemia-in-pregnancy","score":0.3217,"url":"https://openalex.org/keywords/anemia-in-pregnancy"},{"display_name":"iron absorption","id":"iron-absorption","score":0.4686,"url":"https://openalex.org/keywords/iron-absorption"},{"display_name":"hepcidin","id":"hepcidin","score":0.6693,"url":"https://openalex.org/keywords/hepcidin"},{"display_name":"hemoglobin levels","id":"hemoglobin-levels","score":0.2093,"url":"https://openalex.org/keywords/hemoglobin-levels"},{"display_name":"serum iron","id":"serum-iron","score":0.4728,"url":"https://openalex.org/keywords/serum-iron"},{"display_name":"iron homeostasis","id":"iron-homeostasis","score":0.4232,"url":"https://openalex.org/keywords/iron-homeostasis"},{"display_name":"transferrin saturation","id":"transferrin-saturation","score":0.6,"url":"https://openalex.org/keywords/transferrin-saturation"},{"display_name":"iron status","id":"iron-status","score":0.5819,"url":"https://openalex.org/keywords/iron-status"},{"display_name":"transferrin","id":"transferrin","score":0.2532,"url":"https://openalex.org/keywords/transferrin"},{"display_name":"hereditary hemochromatosis","id":"hereditary-hemochromatosis","score":0.8063,"url":"https://openalex.org/keywords/hereditary-hemochromatosis"},{"display_name":"anemia prevalence","id":"anemia-prevalence","score":0.5962,"url":"https://openalex.org/keywords/anemia-prevalence"},{"display_name":"hemochromatosis","id":"hemochromatosis","score":0.5827,"url":"https://openalex.org/keywords/hemochromatosis"},{"display_name":"iron intake","id":"iron-intake","score":0.4114,"url":"https://openalex.org/keywords/iron-intake"},{"display_name":"intravenous iron","id":"intravenous-iron","score":0.4942,"url":"https://openalex.org/keywords/intravenous-iron"},{"display_name":"anemia prevention","id":"anemia-prevention","score":0.3261,"url":"https://openalex.org/keywords/anemia-prevention"},{"display_name":"transferrin receptor","id":"transferrin-receptor","score":0.2419,"url":"https://openalex.org/keywords/transferrin-receptor"},{"display_name":"anemia of chronic disease","id":"anemia-of-chronic-disease","score":0.445,"url":"https://openalex.org/keywords/anemia-of-chronic-disease"},{"display_name":"iron transport","id":"iron-transport","score":0.3937,"url":"https://openalex.org/keywords/iron-transport"}],"legacy_keywords":["Hepcidin","Iron Regulation","Anemia","Ferroportin","Iron Deficiency","Inflammation","Erythropoiesis","Transferrin","Oxidative Stress","Hemochromatosis"],"openalex_id":"https://openalex.org/T10452","source_created_date":"2024-01-23T15:27:06","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2720","url":"/topics/T10452","works_api_url":"https://api.openalex.org/works?filter=topics.id:T10452","works_count":132945,"label":"Iron Metabolism and Disorders","provider":"openalex","revision":"aa1fe41ac27a37e4","taxonomy_revision":"f050b5d4780b1289","title":"Iron Metabolism and Disorders","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36240181489707298","address_version":"morton4x16-v1","coordinates":[4,27,2720,10452],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}