{"cited_by_count":2375176,"description":"This cluster of papers explores the role of oxidative stress, antioxidants, lipid peroxidation, and carotenoids in various health conditions such as atherosclerosis, cardiovascular disease, cancer prevention, and eye health. It investigates the impact of reactive oxygen species, biomarkers of oxidative damage, and the potential use of vitamin E in mitigating oxidative stress-related diseases.","display_name":"Antioxidant Activity and Oxidative Stress","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T10445","wikipedia":"https://en.wikipedia.org/wiki/Oxidative_stress"},"field_id":"27","id":"T10445","keywords":[{"display_name":"vitamin E","id":"vitamin-e","score":0.2248,"url":"https://openalex.org/keywords/vitamin-e"},{"display_name":"alpha-tocopherol","id":"alpha-tocopherol","score":0.2707,"url":"https://openalex.org/keywords/alpha-tocopherol"},{"display_name":"vitamin E deficiency","id":"vitamin-e-deficiency","score":0.4016,"url":"https://openalex.org/keywords/vitamin-e-deficiency"},{"display_name":"dietary antioxidants","id":"dietary-antioxidants","score":0.2034,"url":"https://openalex.org/keywords/dietary-antioxidants"},{"display_name":"lipid hydroperoxides","id":"lipid-hydroperoxides","score":0.2705,"url":"https://openalex.org/keywords/lipid-hydroperoxides"},{"display_name":"vitamin E supplementation","id":"vitamin-e-supplementation","score":0.2731,"url":"https://openalex.org/keywords/vitamin-e-supplementation"},{"display_name":"LDL oxidation","id":"ldl-oxidation","score":0.2034,"url":"https://openalex.org/keywords/ldl-oxidation"},{"display_name":"tocotrienols","id":"tocotrienols","score":0.2859,"url":"https://openalex.org/keywords/tocotrienols"},{"display_name":"antioxidant vitamins","id":"antioxidant-vitamins","score":0.3173,"url":"https://openalex.org/keywords/antioxidant-vitamins"},{"display_name":"gamma-tocopherol","id":"gamma-tocopherol","score":0.2924,"url":"https://openalex.org/keywords/gamma-tocopherol"},{"display_name":"dietary carotenoids","id":"dietary-carotenoids","score":0.4135,"url":"https://openalex.org/keywords/dietary-carotenoids"},{"display_name":"alpha-carotene","id":"alpha-carotene","score":0.3325,"url":"https://openalex.org/keywords/alpha-carotene"},{"display_name":"beta-cryptoxanthin","id":"beta-cryptoxanthin","score":0.2857,"url":"https://openalex.org/keywords/beta-cryptoxanthin"},{"display_name":"lipid peroxidation products","id":"lipid-peroxidation-products","score":0.2521,"url":"https://openalex.org/keywords/lipid-peroxidation-products"},{"display_name":"F2-isoprostanes","id":"f2-isoprostanes","score":0.2199,"url":"https://openalex.org/keywords/f2-isoprostanes"},{"display_name":"carotenoid metabolism","id":"carotenoid-metabolism","score":0.2274,"url":"https://openalex.org/keywords/carotenoid-metabolism"},{"display_name":"copper-induced oxidation","id":"copper-mediated-oxidation","score":0.273,"url":"https://openalex.org/keywords/copper-mediated-oxidation"},{"display_name":"serum carotenoids","id":"serum-carotenoids","score":0.444,"url":"https://openalex.org/keywords/serum-carotenoids"},{"display_name":"prooxidant-antioxidant balance","id":"prooxidant-antioxidant-balance","score":0.2008,"url":"https://openalex.org/keywords/prooxidant-antioxidant-balance"},{"display_name":"antioxidant supplements","id":"antioxidant-supplements","score":0.3315,"url":"https://openalex.org/keywords/antioxidant-supplements"},{"display_name":"plasma carotenoids","id":"plasma-carotenoids","score":0.3562,"url":"https://openalex.org/keywords/plasma-carotenoids"},{"display_name":"serum vitamin E","id":"serum-vitamin-e-levels","score":0.3987,"url":"https://openalex.org/keywords/serum-vitamin-e-levels"},{"display_name":"vitamin E metabolism","id":"vitamin-e-metabolism","score":0.6282,"url":"https://openalex.org/keywords/vitamin-e-metabolism"},{"display_name":"plasma antioxidants","id":"plasma-antioxidants","score":0.3299,"url":"https://openalex.org/keywords/plasma-antioxidants"},{"display_name":"carotenoid bioavailability","id":"carotenoid-bioavailability","score":0.377,"url":"https://openalex.org/keywords/carotenoid-bioavailability"}],"legacy_keywords":["Oxidative Stress","Antioxidants","Lipid Peroxidation","Carotenoids","Vitamin E","Atherosclerosis","Reactive Oxygen Species","Biomarkers","Inflammation","Cancer Prevention"],"openalex_id":"https://openalex.org/T10445","source_created_date":"2024-01-23T15:27:06","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2704","url":"/topics/T10445","works_api_url":"https://api.openalex.org/works?filter=topics.id:T10445","works_count":94413,"label":"Antioxidant Activity and Oxidative Stress","provider":"openalex","revision":"e51e9185d6c95c5c","taxonomy_revision":"f050b5d4780b1289","title":"Antioxidant Activity and Oxidative Stress","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36240181485283626","address_version":"morton4x16-v1","coordinates":[4,27,2704,10445],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}