{"cited_by_count":2783026,"description":"This cluster of papers focuses on the exploration of natural products, particularly from microbial sources, as potential sources of new drugs. It covers various aspects such as genome sequencing, biosynthetic gene clusters, secondary metabolites, and their role in drug discovery. The cluster also emphasizes the significance of marine natural products and the potential of endophytic fungi in providing bioactive compounds for pharmaceutical applications.","display_name":"Microbial Natural Products and Biosynthesis","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T10252","wikipedia":"https://en.wikipedia.org/wiki/Natural_product"},"field_id":"27","id":"T10252","keywords":[{"display_name":"isolation source","id":"isolation-source","score":0.4145,"url":"https://openalex.org/keywords/isolation-source"},{"display_name":"Streptomyces","id":"streptomyces","score":0.9586,"url":"https://openalex.org/keywords/streptomyces"},{"display_name":"myxobacteria","id":"myxobacteria","score":0.4268,"url":"https://openalex.org/keywords/myxobacteria"},{"display_name":"Sorangium cellulosum","id":"sorangium-cellulosum","score":0.9723,"url":"https://openalex.org/keywords/sorangium-cellulosum"},{"display_name":"actinobacteria","id":"actinobacteria","score":0.4435,"url":"https://openalex.org/keywords/actinobacteria"},{"display_name":"fungal secondary metabolites","id":"fungal-secondary-metabolites","score":0.7019,"url":"https://openalex.org/keywords/fungal-secondary-metabolites"},{"display_name":"actinomycetes","id":"actinomycetes","score":0.4097,"url":"https://openalex.org/keywords/actinomycetes"},{"display_name":"endophytic fungi","id":"endophytic-fungi","score":0.3535,"url":"https://openalex.org/keywords/endophytic-fungi"},{"display_name":"biosynthetic gene clusters","id":"biosynthetic-gene-clusters","score":0.7814,"url":"https://openalex.org/keywords/biosynthetic-gene-clusters"},{"display_name":"Streptomyces abikoensis","id":"streptomyces-abikoensis","score":0.9969,"url":"https://openalex.org/keywords/streptomyces-abikoensis"},{"display_name":"Myxococcus fulvus","id":"myxococcus-fulvus","score":0.9797,"url":"https://openalex.org/keywords/myxococcus-fulvus"},{"display_name":"Kitasatospora aureofaciens","id":"kitasatospora-aureofaciens","score":0.944,"url":"https://openalex.org/keywords/kitasatospora-aureofaciens"},{"display_name":"fungal metabolites","id":"fungal-metabolites","score":0.4814,"url":"https://openalex.org/keywords/fungal-metabolites"},{"display_name":"antibiotic biosynthesis","id":"antibiotic-biosynthesis","score":0.6322,"url":"https://openalex.org/keywords/antibiotic-biosynthesis"},{"display_name":"antibiotic production","id":"antibiotic-production","score":0.6913,"url":"https://openalex.org/keywords/antibiotic-production"},{"display_name":"Micromonospora","id":"micromonospora","score":0.8328,"url":"https://openalex.org/keywords/micromonospora"},{"display_name":"natural product biosynthesis","id":"natural-product-biosynthesis","score":0.645,"url":"https://openalex.org/keywords/natural-product-biosynthesis"},{"display_name":"nonribosomal peptide synthetase","id":"nonribosomal-peptide-synthetase","score":0.802,"url":"https://openalex.org/keywords/nonribosomal-peptide-synthetase"},{"display_name":"polyketide synthase","id":"polyketide-synthase","score":0.7029,"url":"https://openalex.org/keywords/polyketide-synthase"},{"display_name":"Myxococcus virescens","id":"myxococcus-virescens","score":0.9795,"url":"https://openalex.org/keywords/myxococcus-virescens"},{"display_name":"fungal natural products","id":"fungal-natural-products","score":0.7696,"url":"https://openalex.org/keywords/fungal-natural-products"},{"display_name":"marine fungi","id":"marine-fungi","score":0.4936,"url":"https://openalex.org/keywords/marine-fungi"},{"display_name":"antibiotic discovery","id":"antibiotic-discovery","score":0.4529,"url":"https://openalex.org/keywords/antibiotic-discovery"},{"display_name":"Myxococcus xanthus","id":"myxococcus-xanthus","score":0.4432,"url":"https://openalex.org/keywords/myxococcus-xanthus"},{"display_name":"Streptomyces griseus","id":"streptomyces-griseus","score":0.6602,"url":"https://openalex.org/keywords/streptomyces-griseus"}],"legacy_keywords":["Natural Products","Drug Discovery","Secondary Metabolites","Antibiotics","Microbial Metabolites","Genome Sequencing","Endophytic Fungi","Marine Natural Products","Nonribosomal Peptides","Polyketide Biosynthesis"],"openalex_id":"https://openalex.org/T10252","source_created_date":"2024-01-23T15:27:05","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2736","url":"/topics/T10252","works_api_url":"https://api.openalex.org/works?filter=topics.id:T10252","works_count":646381,"label":"Microbial Natural Products and Biosynthesis","provider":"openalex","revision":"414dfc14689587fa","taxonomy_revision":"f050b5d4780b1289","title":"Microbial Natural Products and Biosynthesis","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36240179207776546","address_version":"morton4x16-v1","coordinates":[4,27,2736,10252],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}