{"cited_by_count":2894291,"description":"This cluster of papers focuses on the molecular mechanisms, genetic testing, and clinical aspects of cardiac arrhythmias, including Long-QT Syndrome, Brugada Syndrome, and Sudden Cardiac Death. It explores the role of ion channels, calcium signaling, and arrhythmogenic ion-channel remodeling in the heart.","display_name":"Cardiac electrophysiology and arrhythmias","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T10217","wikipedia":"https://en.wikipedia.org/wiki/Cardiac_arrhythmia"},"field_id":"27","id":"T10217","keywords":[{"display_name":"cardiac arrhythmias","id":"cardiac-arrhythmia","score":0.2475,"url":"https://openalex.org/keywords/cardiac-arrhythmia"},{"display_name":"sudden cardiac death","id":"sudden-cardiac-death","score":0.3121,"url":"https://openalex.org/keywords/sudden-cardiac-death"},{"display_name":"ventricular arrhythmias","id":"ventricular-arrhythmias","score":0.3516,"url":"https://openalex.org/keywords/ventricular-arrhythmias"},{"display_name":"cardiac electrophysiology","id":"cardiac-electrophysiology","score":0.5551,"url":"https://openalex.org/keywords/cardiac-electrophysiology"},{"display_name":"antiarrhythmic drugs","id":"antiarrhythmic-drugs","score":0.3514,"url":"https://openalex.org/keywords/antiarrhythmic-drugs"},{"display_name":"ventricular fibrillation","id":"ventricular-fibrillation","score":0.2761,"url":"https://openalex.org/keywords/ventricular-fibrillation"},{"display_name":"Brugada syndrome","id":"brugada-syndrome","score":0.844,"url":"https://openalex.org/keywords/brugada-syndrome"},{"display_name":"long QT syndrome","id":"long-qt-syndrome","score":0.7371,"url":"https://openalex.org/keywords/long-qt-syndrome"},{"display_name":"QT prolongation","id":"qt-interval-prolongation","score":0.5107,"url":"https://openalex.org/keywords/qt-interval-prolongation"},{"display_name":"atrioventricular block","id":"atrioventricular-block","score":0.2701,"url":"https://openalex.org/keywords/atrioventricular-block"},{"display_name":"action potential duration","id":"action-potential-duration","score":0.7301,"url":"https://openalex.org/keywords/action-potential-duration"},{"display_name":"drug-induced arrhythmia","id":"drug-induced-arrhythmia","score":0.5944,"url":"https://openalex.org/keywords/drug-induced-arrhythmia"},{"display_name":"ventricular myocytes","id":"ventricular-myocytes","score":0.5011,"url":"https://openalex.org/keywords/ventricular-myocytes"},{"display_name":"torsades de pointes","id":"torsades-de-pointes","score":0.6813,"url":"https://openalex.org/keywords/torsades-de-pointes"},{"display_name":"sinoatrial node","id":"sinoatrial-node","score":0.5888,"url":"https://openalex.org/keywords/sinoatrial-node"},{"display_name":"premature ventricular contractions","id":"premature-ventricular-contractions","score":0.2704,"url":"https://openalex.org/keywords/premature-ventricular-contractions"},{"display_name":"cardiac conduction disorders","id":"cardiac-conduction-disorders","score":0.3495,"url":"https://openalex.org/keywords/cardiac-conduction-disorders"},{"display_name":"ventricular repolarization","id":"ventricular-repolarization","score":0.6613,"url":"https://openalex.org/keywords/ventricular-repolarization"},{"display_name":"QT interval","id":"qt-interval","score":0.5053,"url":"https://openalex.org/keywords/qt-interval"},{"display_name":"cardiac repolarization","id":"cardiac-repolarization","score":0.619,"url":"https://openalex.org/keywords/cardiac-repolarization"},{"display_name":"cardiac conduction","id":"cardiac-conduction","score":0.5252,"url":"https://openalex.org/keywords/cardiac-conduction"},{"display_name":"antiarrhythmic therapy","id":"antiarrhythmic-therapy","score":0.2415,"url":"https://openalex.org/keywords/antiarrhythmic-therapy"},{"display_name":"calcium handling","id":"calcium-handling","score":0.4121,"url":"https://openalex.org/keywords/calcium-handling"},{"display_name":"calcium transients","id":"calcium-transients","score":0.2997,"url":"https://openalex.org/keywords/calcium-transients"},{"display_name":"excitation-contraction coupling","id":"excitation-contraction-coupling","score":0.3088,"url":"https://openalex.org/keywords/excitation-contraction-coupling"}],"legacy_keywords":["Arrhythmias","Long-QT Syndrome","Sudden Cardiac Death","Ion Channels","Cardiac Electrophysiology","Genetic Testing","Calcium Signaling","Ryanodine Receptor","Brugada Syndrome","Cardiac Channelopathies"],"openalex_id":"https://openalex.org/T10217","source_created_date":"2024-01-23T15:27:05","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2705","url":"/topics/T10217","works_api_url":"https://api.openalex.org/works?filter=topics.id:T10217","works_count":219417,"label":"Cardiac electrophysiology and arrhythmias","provider":"openalex","revision":"a489bd59f377eee6","taxonomy_revision":"f050b5d4780b1289","title":"Cardiac electrophysiology and arrhythmias","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36108824213889326","address_version":"morton4x16-v1","coordinates":[4,27,2705,10217],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}