{"cited_by_count":3566722,"description":"This cluster of papers explores the genetics, epidemiology, pathogenesis, and treatment of inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. It covers topics such as host-microbe interactions, genetic susceptibility loci, immune system involvement, therapeutic targets, and the global burden of these diseases.","display_name":"Inflammatory Bowel Disease","domain_id":"1","external_ids":{"openalex":"https://openalex.org/T10134","wikipedia":"https://en.wikipedia.org/wiki/Inflammatory_bowel_disease"},"field_id":"13","id":"T10134","keywords":[{"display_name":"inflammatory bowel disease","id":"inflammatory-bowel-disease","score":0.544,"url":"https://openalex.org/keywords/inflammatory-bowel-disease"},{"display_name":"Crohn's disease","id":"crohn-s-disease","score":0.6681,"url":"https://openalex.org/keywords/crohn-s-disease"},{"display_name":"ulcerative colitis","id":"ulcerative-colitis","score":0.69,"url":"https://openalex.org/keywords/ulcerative-colitis"},{"display_name":"infliximab","id":"infliximab","score":0.327,"url":"https://openalex.org/keywords/infliximab"},{"display_name":"intestinal inflammation","id":"intestinal-inflammation","score":0.2684,"url":"https://openalex.org/keywords/intestinal-inflammation"},{"display_name":"anti-TNF therapy","id":"anti-tnf-therapy","score":0.319,"url":"https://openalex.org/keywords/anti-tnf-therapy"},{"display_name":"DSS-induced colitis","id":"dss-induced-colitis","score":0.5732,"url":"https://openalex.org/keywords/dss-induced-colitis"},{"display_name":"pediatric inflammatory bowel disease","id":"pediatric-inflammatory-bowel-disease","score":0.826,"url":"https://openalex.org/keywords/pediatric-inflammatory-bowel-disease"},{"display_name":"5-aminosalicylic acid","id":"5-aminosalicylic-acid","score":0.4996,"url":"https://openalex.org/keywords/5-aminosalicylic-acid"},{"display_name":"colitis","id":"colitis","score":0.284,"url":"https://openalex.org/keywords/colitis"},{"display_name":"fecal calprotectin","id":"fecal-calprotectin","score":0.6571,"url":"https://openalex.org/keywords/fecal-calprotectin"},{"display_name":"clinical remission","id":"clinical-remission","score":0.4122,"url":"https://openalex.org/keywords/clinical-remission"},{"display_name":"vedolizumab","id":"vedolizumab","score":0.782,"url":"https://openalex.org/keywords/vedolizumab"},{"display_name":"extraintestinal manifestations","id":"extraintestinal-manifestations","score":0.5321,"url":"https://openalex.org/keywords/extraintestinal-manifestations"},{"display_name":"mucosal healing","id":"mucosal-healing","score":0.6059,"url":"https://openalex.org/keywords/mucosal-healing"},{"display_name":"colectomy","id":"colectomy","score":0.3083,"url":"https://openalex.org/keywords/colectomy"},{"display_name":"ileal pouch-anal anastomosis","id":"ileal-pouch-anal-anastomosis","score":0.7336,"url":"https://openalex.org/keywords/ileal-pouch-anal-anastomosis"},{"display_name":"ustekinumab","id":"ustekinumab","score":0.4131,"url":"https://openalex.org/keywords/ustekinumab"},{"display_name":"pediatric Crohn's disease","id":"pediatric-crohn-s-disease","score":0.8765,"url":"https://openalex.org/keywords/pediatric-crohn-s-disease"},{"display_name":"colonic inflammation","id":"colonic-inflammation","score":0.4283,"url":"https://openalex.org/keywords/colonic-inflammation"},{"display_name":"TNBS-induced colitis","id":"tnbs-induced-colitis","score":0.6299,"url":"https://openalex.org/keywords/tnbs-induced-colitis"},{"display_name":"pouchitis","id":"pouchitis","score":0.8179,"url":"https://openalex.org/keywords/pouchitis"},{"display_name":"disease activity assessment","id":"disease-activity-assessment","score":0.2075,"url":"https://openalex.org/keywords/disease-activity-assessment"},{"display_name":"colonic mucosa","id":"colonic-mucosa","score":0.2406,"url":"https://openalex.org/keywords/colonic-mucosa"},{"display_name":"sulfasalazine","id":"sulfasalazine","score":0.2318,"url":"https://openalex.org/keywords/sulfasalazine"}],"legacy_keywords":["Inflammatory Bowel Disease","Crohn's Disease","Ulcerative Colitis","Genetics","Immunology","Therapies","Epidemiology","Pathogenesis","Biological Therapies","Mucosal Healing"],"openalex_id":"https://openalex.org/T10134","source_created_date":"2024-01-23T15:27:05","source_updated_date":"2026-10-17T03:02:00","subfield_id":"1311","url":"/topics/T10134","works_api_url":"https://api.openalex.org/works?filter=topics.id:T10134","works_count":229491,"label":"Inflammatory Bowel Disease","provider":"openalex","revision":"a3d38b3ee2e6f3b1","taxonomy_revision":"f050b5d4780b1289","title":"Inflammatory Bowel Disease","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36042594602217159","address_version":"morton4x16-v1","coordinates":[1,13,1311,10134],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}