{"cited_by_count":3182664,"description":"This cluster of papers focuses on the genetics, classification, treatment, and epidemiology of gliomas, particularly glioblastoma and medulloblastoma. It covers topics such as the molecular pathways, mutations (e.g., IDH), treatment strategies (e.g., temozolomide, radiotherapy), and the use of immunotherapy in neuro-oncology.","display_name":"Glioma Diagnosis and Treatment","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T10129","wikipedia":"https://en.wikipedia.org/wiki/Glioma"},"field_id":"27","id":"T10129","keywords":[{"display_name":"glioblastoma","id":"glioblastoma","score":0.5224,"url":"https://openalex.org/keywords/glioblastoma"},{"display_name":"glioma","id":"glioma","score":0.4204,"url":"https://openalex.org/keywords/glioma"},{"display_name":"brain tumors","id":"brain-tumors","score":0.3374,"url":"https://openalex.org/keywords/brain-tumors"},{"display_name":"pediatric brain tumors","id":"pediatric-brain-tumors","score":0.6344,"url":"https://openalex.org/keywords/pediatric-brain-tumors"},{"display_name":"temozolomide","id":"temozolomide","score":0.5871,"url":"https://openalex.org/keywords/temozolomide"},{"display_name":"high-grade glioma","id":"high-grade-glioma","score":0.5941,"url":"https://openalex.org/keywords/high-grade-glioma"},{"display_name":"medulloblastoma","id":"medulloblastoma","score":0.5772,"url":"https://openalex.org/keywords/medulloblastoma"},{"display_name":"astrocytoma","id":"astrocytoma","score":0.5826,"url":"https://openalex.org/keywords/astrocytoma"},{"display_name":"central nervous system tumors","id":"central-nervous-system-tumors","score":0.4186,"url":"https://openalex.org/keywords/central-nervous-system-tumors"},{"display_name":"low-grade glioma","id":"low-grade-glioma","score":0.6332,"url":"https://openalex.org/keywords/low-grade-glioma"},{"display_name":"recurrent glioblastoma","id":"recurrent-glioblastoma","score":0.8321,"url":"https://openalex.org/keywords/recurrent-glioblastoma"},{"display_name":"oligodendroglioma","id":"oligodendroglioma","score":0.7498,"url":"https://openalex.org/keywords/oligodendroglioma"},{"display_name":"MGMT promoter methylation","id":"mgmt-promoter-methylation","score":0.8048,"url":"https://openalex.org/keywords/mgmt-promoter-methylation"},{"display_name":"extent of resection","id":"extent-of-resection","score":0.3733,"url":"https://openalex.org/keywords/extent-of-resection"},{"display_name":"ependymoma","id":"ependymoma","score":0.6263,"url":"https://openalex.org/keywords/ependymoma"},{"display_name":"glioma stem cells","id":"glioma-stem-cells","score":0.6101,"url":"https://openalex.org/keywords/glioma-stem-cells"},{"display_name":"anaplastic astrocytoma","id":"anaplastic-astrocytoma","score":0.7824,"url":"https://openalex.org/keywords/anaplastic-astrocytoma"},{"display_name":"1p/19q codeletion","id":"1p-19q-codeletion","score":0.8635,"url":"https://openalex.org/keywords/1p-19q-codeletion"},{"display_name":"pilocytic astrocytoma","id":"pilocytic-astrocytoma","score":0.7518,"url":"https://openalex.org/keywords/pilocytic-astrocytoma"},{"display_name":"recurrent glioma","id":"recurrent-glioma","score":0.7804,"url":"https://openalex.org/keywords/recurrent-glioma"},{"display_name":"IDH mutation","id":"idh-mutation","score":0.6516,"url":"https://openalex.org/keywords/idh-mutation"},{"display_name":"IDH1 mutation","id":"idh1-mutation","score":0.4983,"url":"https://openalex.org/keywords/idh1-mutation"},{"display_name":"neuro-oncology","id":"neuro-oncology","score":0.4218,"url":"https://openalex.org/keywords/neuro-oncology"},{"display_name":"diffuse intrinsic pontine glioma","id":"diffuse-intrinsic-pontine-glioma","score":0.7556,"url":"https://openalex.org/keywords/diffuse-intrinsic-pontine-glioma"},{"display_name":"cerebellar tumor","id":"cerebellar-tumor","score":0.5518,"url":"https://openalex.org/keywords/cerebellar-tumor"}],"legacy_keywords":["Glioblastoma","Temozolomide","IDH Mutation","Radiotherapy","Molecular Classification","MGMT Promoter Methylation","Medulloblastoma","Brain Tumor Epidemiology","Immunotherapy","Neuro-Oncology"],"openalex_id":"https://openalex.org/T10129","source_created_date":"2024-01-23T15:27:05","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2716","url":"/topics/T10129","works_api_url":"https://api.openalex.org/works?filter=topics.id:T10129","works_count":211981,"label":"Glioma Diagnosis and Treatment","provider":"openalex","revision":"2e6eed9da201381d","taxonomy_revision":"f050b5d4780b1289","title":"Glioma Diagnosis and Treatment","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36108824071791914","address_version":"morton4x16-v1","coordinates":[4,27,2716,10129],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}